Search on: OLIGODEOXYRIBONUCLEOTIDE PROBES 
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Descriptor English:   Oligonucleotide Probes 
Descriptor Spanish:   Sondas de Oligonucleótidos 
Descriptor Portuguese:   Sondas de Oligonucleotídeos 
Synonyms English:   Oligodeoxyribonucleotide Probes
Oligoribonucleotide Probes  
Tree Number:   D13.444.600.601
D27.720.470.530.600.650
Definition English:   Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin. 
Indexing Annotation English:   usually no qualif; /drug eff /ultrastruct permitted
See Related English:   Nucleic Acid Hybridization
Oligonucleotide Array Sequence Analysis
 
History Note English:   89 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
drug effects diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   23787 
Unique Identifier:   D015345 

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